Flavonoids of Melaleuca quinquenervia

Pharmazie. 2001 Jan;56(1):94-5. doi: 10.1002/chin.200117207.


From the leaves of Melaleuca quinquenervia (Clav.) S. T. Blake, the new flavonoid 5,7,3',4'-tetrahydroxyflavone 2'-O-beta-D-glucopyranuronide, as well as eight known flavonol glycosides have been isolated and characterized. The structures were established by chromatography, chemical degradation and UV spectroscopy and confirmed by ESI-MS and NMR spectroscopy. This is the first report on the isolation and identification of these flavonoids in the genus Melaleuca.

MeSH terms

  • Flavonoids / analysis*
  • Flavonoids / isolation & purification
  • Magnetic Resonance Spectroscopy
  • Spectrometry, Mass, Electrospray Ionization
  • Spectrophotometry, Ultraviolet
  • Tea Tree Oil / analysis*


  • 5,7,3',4'-tetrahydroxyflavone 2'-O-glucopyranuronide
  • Flavonoids
  • Tea Tree Oil