Symptomatic splenic hamartoma with renal, cutaneous, and hematological abnormalities

Pediatr Radiol. 2001 Feb;31(2):111-4. doi: 10.1007/s002470000382.


Background: There is a rare association between splenic hamartomas and hematological abnormalities with, to our knowledge, only 24 reported cases in the English literature.

Patients and methods: We report a case of a splenic hamartoma in a 14-year-old boy associated with membranoproliferative glomerulonephritis, multiple lobular capillary hemangiomas of the skin, hypertension, and anemia. Following imaging with ultrasonography, MRI, and nuclear scans, a hamartoma was suspected, but malignancy could not be excluded. The lesion was removed by partial splenectomy, and pathological examination confirmed the presence of a red pulp splenic hamartoma.

Results: The renal, hematological, and dermatological abnormalities resolved following removal of the splenic hamartoma. This is the first reported case of a splenic hamartoma associated with renal, cutaneous, and hematological abnormalities and only the second reported case of a symptomatic splenic hamartoma treated by partial splenectomy.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Diagnosis, Differential
  • Diagnostic Imaging
  • Hamartoma / complications*
  • Hamartoma / diagnosis*
  • Hamartoma / surgery
  • Humans
  • Male
  • Splenic Diseases / complications*
  • Splenic Diseases / diagnosis*
  • Splenic Diseases / surgery