Cytotoxins Directed at interleukin-4 Receptors as Therapy for Human Brain Tumors

Methods Mol Biol. 2001;166:155-76. doi: 10.1385/1-59259-114-0:155.

Publication types

  • Comparative Study
  • Review

MeSH terms

  • ADP Ribose Transferases*
  • Animals
  • Antineoplastic Agents / chemistry
  • Antineoplastic Agents / pharmacology
  • Antineoplastic Agents / therapeutic use*
  • Bacterial Toxins*
  • Brain Neoplasms / drug therapy*
  • Brain Neoplasms / metabolism
  • Brain Neoplasms / pathology
  • Clinical Trials, Phase I as Topic
  • Exotoxins / therapeutic use*
  • Glioblastoma / drug therapy
  • Glioblastoma / metabolism
  • Glioblastoma / pathology
  • Glioma / drug therapy*
  • Glioma / metabolism
  • Glioma / pathology
  • Guinea Pigs
  • Humans
  • Immunotoxins / administration & dosage
  • Immunotoxins / pharmacology
  • Immunotoxins / therapeutic use*
  • Injections, Intralesional
  • Injections, Intraperitoneal
  • Injections, Intravenous
  • Injections, Spinal
  • Interleukin-4 / physiology*
  • Macaca fascicularis
  • Mice
  • Mice, Nude
  • Neoplasm Proteins / chemistry
  • Neoplasm Proteins / drug effects*
  • Neuroblastoma / drug therapy
  • Neuroblastoma / metabolism
  • Neuroblastoma / pathology
  • Protein Structure, Tertiary
  • Rats
  • Receptors, Interleukin-4 / chemistry
  • Receptors, Interleukin-4 / drug effects*
  • Treatment Outcome
  • Tumor Stem Cell Assay
  • Virulence Factors*
  • Xenograft Model Antitumor Assays

Substances

  • Antineoplastic Agents
  • Bacterial Toxins
  • Exotoxins
  • Immunotoxins
  • Neoplasm Proteins
  • Receptors, Interleukin-4
  • Virulence Factors
  • interleukin 4 (38-37)-PE38KDEL
  • Interleukin-4
  • ADP Ribose Transferases
  • toxA protein, Pseudomonas aeruginosa