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. 2000 Dec;53(12):1341-5.
doi: 10.7164/antibiotics.53.1341.

FR191512, a novel anti-influenza agent isolated from a fungus strain No.17415. II. Biological properties

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Free article

FR191512, a novel anti-influenza agent isolated from a fungus strain No.17415. II. Biological properties

Y Nishihara et al. J Antibiot (Tokyo). 2000 Dec.
Free article

Abstract

FR191512, a novel polyphenolic compound, inhibited the infectivity of influenza A virus in Madin-Darby canine kidney (MDCK) cells in vitro. Furthermore, FR191512 showed good in vivo anti-influenza activity in a mouse model of intranasal infection with influenza A virus. The cytotoxic activity of FR191512 against MDCK cells was very weak.

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