Functional annotation of a full-length mouse cDNA collection

Nature. 2001 Feb 8;409(6821):685-90. doi: 10.1038/35055500.


The RIKEN Mouse Gene Encyclopaedia Project, a systematic approach to determining the full coding potential of the mouse genome, involves collection and sequencing of full-length complementary DNAs and physical mapping of the corresponding genes to the mouse genome. We organized an international functional annotation meeting (FANTOM) to annotate the first 21,076 cDNAs to be analysed in this project. Here we describe the first RIKEN clone collection, which is one of the largest described for any organism. Analysis of these cDNAs extends known gene families and identifies new ones.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Chromosome Mapping
  • Computational Biology*
  • DNA, Complementary*
  • Enzymes / genetics
  • Gene Library
  • Genome
  • Humans
  • Mice / genetics*
  • Mice, Inbred C57BL
  • Protein Biosynthesis
  • Protein Structure, Tertiary
  • RNA, Messenger
  • Sequence Analysis, DNA


  • DNA, Complementary
  • Enzymes
  • RNA, Messenger