GeneSplicer: a new computational method for splice site prediction

Nucleic Acids Res. 2001 Mar 1;29(5):1185-90. doi: 10.1093/nar/29.5.1185.


GeneSplicer is a new, flexible system for detecting splice sites in the genomic DNA of various eukaryotes. The system has been tested successfully using DNA from two reference organisms: the model plant Arabidopsis thaliana and human. It was compared to six programs representing the leading splice site detectors for each of these species: NetPlantGene, NetGene2, HSPL, NNSplice, GENIO and SpliceView. In each case GeneSplicer performed comparably to the best alternative, in terms of both accuracy and computational efficiency.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Algorithms*
  • Alternative Splicing / genetics*
  • Arabidopsis / genetics
  • Computational Biology / methods*
  • DNA / genetics
  • Databases, Factual
  • Genes / genetics
  • Genome, Human
  • Genome, Plant
  • Humans


  • DNA