The present status of exogenous surfactant for the newborn

Early Hum Dev. 2001 Mar;61(2):67-83. doi: 10.1016/s0378-3782(00)00122-5.

Abstract

This year is the 20th anniversary of the first successful trial of exogenous surfactant for respiratory distress syndrome in the newborn and it is perhaps a good time to review recent advances in basic science and clinical practice as they relate to surfactant therapy.

Publication types

  • Review

MeSH terms

  • Animals
  • Glycoproteins / deficiency
  • Glycoproteins / physiology
  • Humans
  • Infant, Newborn
  • Infant, Premature
  • Lung Diseases / drug therapy
  • Mice
  • Mice, Transgenic
  • Proteolipids / physiology
  • Pulmonary Surfactant-Associated Protein D
  • Pulmonary Surfactant-Associated Proteins
  • Pulmonary Surfactants / deficiency
  • Pulmonary Surfactants / physiology
  • Pulmonary Surfactants / therapeutic use*
  • Recombinant Proteins / therapeutic use
  • Respiratory Distress Syndrome, Newborn / drug therapy

Substances

  • Glycoproteins
  • Proteolipids
  • Pulmonary Surfactant-Associated Protein D
  • Pulmonary Surfactant-Associated Proteins
  • Pulmonary Surfactants
  • Recombinant Proteins