Two distinct modes of sensory processing observed in monkey primary visual cortex (V1)

Nat Neurosci. 2001 Mar;4(3):304-10. doi: 10.1038/85170.


Even salient sensory stimuli are sometimes not detected. What goes wrong in the brain in that case? Here we show that a late (> 100-ms) component of the neural activity in the primary visual cortex of the monkey is selectively suppressed when stimuli are not seen. As there is evidence that this activity depends on feedback from extrastriate areas, these findings suggest a specific role for recurrent processing when stimuli are reaching a perceptual level. Further results show that this perceptual level is situated between purely sensory and decision or motor stages of processing.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Action Potentials / physiology
  • Animals
  • Macaca mulatta / anatomy & histology
  • Macaca mulatta / physiology
  • Models, Neurological
  • Neurons / cytology
  • Neurons / physiology*
  • Normal Distribution
  • Pattern Recognition, Visual / physiology*
  • Photic Stimulation
  • Psychomotor Performance / physiology*
  • Reaction Time / physiology
  • Saccades / physiology
  • Visual Cortex / cytology
  • Visual Cortex / physiology*
  • Visual Pathways / cytology
  • Visual Pathways / physiology*