Stevens-Johnson syndrome and toxic epidermal necrolysis after vaccination: reports to the vaccine adverse event reporting system

R Ball; L K Ball; R P Wise; M M Braun; J A Beeler; M E Salive

doi:10.1097/00006454-200102000-00022

Stevens-Johnson syndrome and toxic epidermal necrolysis after vaccination: reports to the vaccine adverse event reporting system

Pediatr Infect Dis J. 2001 Feb;20(2):219-23. doi: 10.1097/00006454-200102000-00022.

Authors

R Ball¹, L K Ball, R P Wise, M M Braun, J A Beeler, M E Salive

Affiliation

¹ The Vaers Working Group Office of Biostatistics and Epidemiology, Center for Biologics Evaluation and Research, Food and Drug Administration, Rockville, MD, USA. BallR@cber.fda.gov

PMID: 11224848
DOI: 10.1097/00006454-200102000-00022

Abstract

We conducted a telephone survey of reports of Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) to the Vaccine Adverse Event Reporting System. We identified six cases of SJS or TEN after vaccination without other obvious triggers, suggesting that SJS and TEN might very rarely be caused by vaccination. Confirmation of this hypothesis will likely require controlled studies.

Publication types

Case Reports

MeSH terms

Adult
Adverse Drug Reaction Reporting Systems / statistics & numerical data*
Child, Preschool
Female
Follow-Up Studies
Humans
Infant
Male
Stevens-Johnson Syndrome / etiology*
Telephone
Vaccination / adverse effects*