[Neuraminidase inhibitor]

Nihon Rinsho. 2000 Nov;58(11):2293-8.
[Article in Japanese]


Amantadine, effective to influenza A virus, is now widely used in Japan. Recently new anti-influenzal agents, neuramidase inhibitor has been developed. Both Zanamivir (inhaled type) and Oseltamivir(oral use), are proved to be effective in treatment of influenza A and B. Mechanism of action on influenza virus, dosage, side effects of the anti-influenza agents are described. Clinicians expect to medicate to influenza with the agents as soon as possible.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Acetamides / therapeutic use*
  • Antiviral Agents / therapeutic use*
  • Enzyme Inhibitors / therapeutic use*
  • Guanidines
  • Humans
  • Influenza A virus*
  • Influenza B virus*
  • Influenza, Human / drug therapy*
  • Neuraminidase / antagonists & inhibitors*
  • Oseltamivir
  • Pyrans
  • Sialic Acids / therapeutic use*
  • Zanamivir


  • Acetamides
  • Antiviral Agents
  • Enzyme Inhibitors
  • Guanidines
  • Pyrans
  • Sialic Acids
  • Oseltamivir
  • Neuraminidase
  • Zanamivir