Oxidant-antioxidant status in acute and chronic renal failure

Indian J Med Sci. 2000 Apr;54(4):131-5.

Abstract

Present study was carried out to evaluate oxidant-antioxidant status and effect of hemodialysis in acute and chronic renal failure. Serum MDA levels increased while serum SOD found decreased significantly. This study indicates the existence and increased production of an oxidizing stress resulting from hemodialysis and disturbance in antioxidant enzyme system.

MeSH terms

  • Acute Kidney Injury / blood*
  • Acute Kidney Injury / enzymology
  • Acute Kidney Injury / metabolism
  • Adult
  • Case-Control Studies
  • Female
  • Free Radical Scavengers / blood*
  • Free Radical Scavengers / metabolism
  • Humans
  • Kidney Failure, Chronic / blood*
  • Kidney Failure, Chronic / enzymology
  • Kidney Failure, Chronic / metabolism
  • Lipid Peroxidation
  • Male
  • Malondialdehyde / blood*
  • Middle Aged
  • Renal Dialysis / adverse effects*
  • Superoxide Dismutase / blood*
  • Superoxide Dismutase / metabolism
  • Treatment Outcome

Substances

  • Free Radical Scavengers
  • Malondialdehyde
  • Superoxide Dismutase