Parinaud's oculoglandular syndrome attributable to an encounter with a wild rabbit

Am J Ophthalmol. 2001 Feb;131(2):283-4. doi: 10.1016/s0002-9394(00)00954-5.


Purpose: To describe the clinical and histopathologic findings in a patient with Parinaud's oculoglandular syndrome attributable to Francisella tularensis obtained from an encounter with a wild baby rabbit.

Methods: In an 18-year-old man, the clinical course, laboratory findings, and histopathologic findings are described.

Results: Parinaud's oculoglandular syndrome should be considered in the differential diagnosis of a patient presenting with unilateral granulomatous conjunctivitis, painful preauricular, and submandibular lymphadenopathy combined with systemic symptoms of general malaise and fever.

Conclusion: Tularemia is one etiology of Parinaud's oculoglandular syndrome. It is caused by Francisella tularensis and is usually transmitted to humans via infected animal blood or through an insect bite, most often a tick. For treatment, intramuscular streptomycin is the drug of choice.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Animals
  • Animals, Wild / microbiology*
  • Conjunctivitis, Bacterial / diagnosis
  • Conjunctivitis, Bacterial / drug therapy
  • Conjunctivitis, Bacterial / microbiology*
  • Drug Therapy, Combination / therapeutic use
  • Francisella tularensis / isolation & purification*
  • Humans
  • Injections, Intramuscular
  • Injections, Intravenous
  • Male
  • Nafcillin / administration & dosage
  • Rabbits / microbiology*
  • Streptomycin / administration & dosage
  • Tularemia / diagnosis
  • Tularemia / drug therapy
  • Tularemia / microbiology*
  • Zoonoses / microbiology*


  • Nafcillin
  • Streptomycin