Acute and long-term treatment of catatonia with risperidone

Pharmacopsychiatry. 2001 Jan;34(1):25-6. doi: 10.1055/s-2001-15190.


Catatonia is a rare but difficult-to-treat disorder. Here, we report on the case of a schizophrenic patient who developed several episodes of severe catatonia after suffering from adequately treated Lyme disease with encephalitis. The catatonic stupor was not responsive to typical neuroleptics and benzodiazepines. After the medication was changed to risperidone, there was a dramatic and persistent improvement of the patient's condition. Two relapses during the follow-up period over five years were caused by dose reductions. Risperidone might be a promising drug in the treatment of acute catatonia and in preventing further episodes.

Publication types

  • Case Reports

MeSH terms

  • Acute Disease
  • Adult
  • Antipsychotic Agents / adverse effects
  • Antipsychotic Agents / therapeutic use*
  • Dyskinesia, Drug-Induced / psychology
  • Humans
  • Long-Term Care
  • Male
  • Risperidone / adverse effects
  • Risperidone / therapeutic use*
  • Schizophrenia, Catatonic / drug therapy*
  • Schizophrenia, Catatonic / psychology


  • Antipsychotic Agents
  • Risperidone