Effect of antipyretic drugs in children with malaria

B Lell; M Sovric; D Schmid; D Luckner; K Herbich; H Y Long; W Graninger; P G Kremsner

doi:10.1086/319217

Effect of antipyretic drugs in children with malaria

Clin Infect Dis. 2001 Mar 1;32(5):838-41. doi: 10.1086/319217. Epub 2001 Feb 23.

Authors

B Lell¹, M Sovric, D Schmid, D Luckner, K Herbich, H Y Long, W Graninger, P G Kremsner

Affiliation

¹ Research Unit, Albert Schweitzer Hospital, Lambaréné, Gabon; Department of Parasitology, Institute of Tropical Medicine, University of Tübingen, Tübingen, Germany.

PMID: 11229858
DOI: 10.1086/319217

Abstract

A comparison of different antipyretics in children with malaria showed a small effect of naproxen, but not of metamizol, on the reduction of fever peaks. Antipyretic treatment had no effect on fever clearance and therefore should be used cautiously in the treatment of malaria.

Publication types

Clinical Trial
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

MeSH terms

Analgesics, Non-Narcotic / therapeutic use*
Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
Child
Child, Preschool
Dipyrone / therapeutic use
Fever / drug therapy*
Humans
Malaria, Falciparum / parasitology
Malaria, Falciparum / physiopathology*
Naproxen / therapeutic use
Parasitemia / parasitology
Parasitemia / physiopathology*

Substances

Analgesics, Non-Narcotic
Anti-Inflammatory Agents, Non-Steroidal
Naproxen
Dipyrone