Enhanced detection of right-to-left shunt through patent foramen ovale by transthoracic contrast echocardiography using harmonic imaging

Am J Cardiol. 2001 Mar 1;87(5):669-71, A11. doi: 10.1016/s0002-9149(00)01455-7.


When the results of transesophageal echocardiography was regarded as the gold standard for detecting a patent foramen ovale (PFO) in 136 consecutive patients referred for evaluation of cardiac source of embolism, transthoracic harmonic imaging using saline contrast was superior to fundamental imaging in accuracy for detecting a PFO (sensitivity, 22.5%; specificity [p < 0.05] and sensitivity, 100%; specificity 100%, respectively.)

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Echocardiography*
  • Echocardiography, Transesophageal
  • Embolism, Paradoxical / diagnostic imaging*
  • Female
  • Heart Septal Defects, Atrial / diagnostic imaging*
  • Humans
  • Image Enhancement*
  • Male
  • Middle Aged
  • Predictive Value of Tests