Functional Genomics: The Worm Scores a Knockout

Curr Biol. 2001 Feb 6;11(3):R85-7. doi: 10.1016/s0960-9822(01)00035-5.


Following the completion of the genome sequence of Caenorhabditis elegans, four independent studies have now assessed the functions of more than a third of the worm's genes by analysing the phenotypes caused when each of a large set of genes is inactivated by RNA interference.

Publication types

  • Review

MeSH terms

  • Animals
  • Caenorhabditis elegans / genetics*
  • Gene Silencing
  • Genome*
  • Phenotype