Membrane transport: retromer to the rescue

Curr Biol. 2001 Feb 6;11(3):R109-11. doi: 10.1016/s0960-9822(01)00042-2.


Genetic analysis in yeast has led to the discovery of a complex that retrieves proteins selectively from the prevacuolar compartment and transports them to the Golgi. Orthologs of these proteins in mammalian cells are likely to play a similar role but their cargoes are yet to be identified.

Publication types

  • Review

MeSH terms

  • Animals
  • Cell Compartmentation
  • Cell Membrane / metabolism*
  • Fungal Proteins / metabolism
  • Golgi Apparatus / metabolism
  • Protein Transport
  • Receptors, Cell Surface / metabolism
  • Saccharomyces cerevisiae Proteins*
  • Vesicular Transport Proteins*


  • Fungal Proteins
  • PEP1 protein, S cerevisiae
  • Receptors, Cell Surface
  • Saccharomyces cerevisiae Proteins
  • Vesicular Transport Proteins