Polymorphic ventricular tachycardia, long Q-T syndrome, and torsades de pointes

Med Clin North Am. 2001 Mar;85(2):321-41. doi: 10.1016/s0025-7125(05)70318-7.


PMVT is an uncommon arrhythmia with multiple causes. Classification and management are based on the Q-T interval. Torsades de pointes denotes PMVT in the setting of a prolonged Q-T interval and usually is iatrogenic in origin, although congenital LQTS is being recognized more frequently. Therapy of PMVT focuses on the establishment of hemodynamic stability, the removal or correction of precipitants, and the acute and long-term inhibition of subsequent episodes. Evaluation of these patients should include a thorough history and physical examination and an assessment for underlying heart disease and known [figure: see text] eliciting factors. Long-term management must be tailored to the individual and the underlying cause and should be conducted by an experienced cardiac electrophysiologist.

Publication types

  • Evaluation Study
  • Review

MeSH terms

  • Anti-Arrhythmia Agents / therapeutic use
  • Cardiac Pacing, Artificial
  • Defibrillators, Implantable
  • Diagnosis, Differential
  • Disease Susceptibility
  • Electrocardiography
  • Ganglionectomy
  • Heart Rate
  • Humans
  • Long QT Syndrome* / diagnosis
  • Long QT Syndrome* / etiology
  • Long QT Syndrome* / physiopathology
  • Long QT Syndrome* / therapy
  • Prognosis
  • Stellate Ganglion / surgery
  • Tachycardia, Ventricular* / diagnosis
  • Tachycardia, Ventricular* / etiology
  • Tachycardia, Ventricular* / physiopathology
  • Tachycardia, Ventricular* / therapy
  • Torsades de Pointes* / diagnosis
  • Torsades de Pointes* / etiology
  • Torsades de Pointes* / physiopathology
  • Torsades de Pointes* / therapy


  • Anti-Arrhythmia Agents