Workflow analysis is an ongoing process for laboratory managers. Throughout the years, laboratory managers have made many changes such as creating a core laboratory, consolidating technology, and implementing a new laboratory information system, all of which will have an immediate impact on laboratory operations. However, after implementation of any change in the laboratory, one should follow up with a pre- and/or postanalytical workflow assessment. This case study evaluates the pre-analytical impact of analytical changes made more than a year ago.