Bioactive factors in human milk

Pediatr Clin North Am. 2001 Feb;48(1):69-86. doi: 10.1016/s0031-3955(05)70286-8.


This article reviews the bioactive components of human milk. Special emphasis is given to immune and nonimmune protective function of major and minor nutrients in human milk. Immune modulating components, such as cytokines, nucleotides, hormones, and growth factors, are discussed. Milk enzymes with digestive function in the newborn are reviewed.

Publication types

  • Review

MeSH terms

  • Humans
  • Infant Nutritional Physiological Phenomena / physiology
  • Infant, Newborn
  • Lactoferrin / physiology
  • Lipids / physiology
  • Milk, Human / cytology
  • Milk, Human / immunology
  • Milk, Human / physiology*
  • Prolactin / physiology


  • Lipids
  • Prolactin
  • Lactoferrin