Mitochondrial DNA variant 11719G is a marker for the mtDNA haplogroup cluster HV

Hum Biol. 2000 Dec;72(6):1065-8.


Based on sequencing data and results obtained from applying a tailored mismatch polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) analysis, we report that the G allele of the mitochondrial DNA (mtDNA) polymorphism at nucleotide position 11719 is associated with the European mtDNA haplogroup cluster HV, and that 11719A is therefore the ancestral allele.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • DNA, Mitochondrial / genetics*
  • Denmark
  • Genetic Markers
  • Haplotypes / genetics*
  • Humans
  • Optic Atrophies, Hereditary / genetics
  • Polymorphism, Genetic*


  • DNA, Mitochondrial
  • Genetic Markers