Amyotrophic lateral sclerosis. unfolding the toxicity of the misfolded

Cell. 2001 Feb 23;104(4):581-91. doi: 10.1016/s0092-8674(01)00244-6.

Author

J P Julien¹

Affiliation

¹ Centre for Research in Neurosciences, McGill University, The Montreal General Hospital Research Institute, Québec, H3G 1A4, Montréal, Canada. mdju@musica.mcgill.ca

PMID: 11239414
DOI: 10.1016/s0092-8674(01)00244-6

No abstract available

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Amyotrophic Lateral Sclerosis / etiology*
Amyotrophic Lateral Sclerosis / genetics*
Amyotrophic Lateral Sclerosis / metabolism*
Animals
Apoptosis
Cell Death
Copper / metabolism
Cytoskeleton / chemistry
Cytoskeleton / genetics
Humans
Mice
Mitochondria / metabolism
Models, Biological
Motor Neurons / pathology
Mutation, Missense
Neurofilament Proteins / metabolism
Risk Factors
Superoxide Dismutase / chemistry
Superoxide Dismutase / genetics
Superoxide Dismutase-1

Substances

Neurofilament Proteins
SOD1 protein, human
Copper
Sod1 protein, mouse
Superoxide Dismutase
Superoxide Dismutase-1