Vacuolar H+/Ca2+ transport: who's directing the traffic?

Trends Plant Sci. 2001 Mar;6(3):100-4. doi: 10.1016/s1360-1385(00)01863-x.


Physiological studies have established the role of plant high-capacity vacuolar H+/Ca2+ exchange activity in ion homeostasis and signal transduction. The molecular characterization and structure-function analyses of these transporters are just beginning to emerge. In yeast, Ca2+ signaling molecules regulate vacuolar H+/Ca2+ exchange. Recently, some of the Ca2+ dependent "molecular relay" molecules have been characterized in plants; however, the regulation of plant vacuolar H+/Ca2+ exchange remains an open question.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Calcium / metabolism*
  • Carrier Proteins / metabolism
  • Gene Expression
  • Genes, Plant
  • Hydrogen / metabolism*
  • Ion Transport
  • Vacuoles / metabolism*


  • Carrier Proteins
  • Hydrogen
  • Calcium