Functions of mammalian spinal interneurons during movement

Curr Opin Neurobiol. 2000 Dec;10(6):699-707. doi: 10.1016/s0959-4388(00)00160-4.


The major recent advances in understanding the role of spinal neurons in generating movement include new information about the modulation of classic reflex pathways during fictive locomotion and in response to pharmacological probes. The possibility of understanding movements in terms of spinal representations of a basic set of movement primitives has been extended by the analysis of normal reflexes. Recordings of the activity of cervical interneurons in behaving monkeys has elucidated their contribution to generating voluntary movement and revealed their involvement in movement preparation.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Interneurons / physiology*
  • Mammals
  • Movement / physiology*
  • Spinal Cord / cytology*
  • Spinal Cord / physiology*