Mechanisms of cerebellar learning suggested by eyelid conditioning

Curr Opin Neurobiol. 2000 Dec;10(6):717-24. doi: 10.1016/s0959-4388(00)00154-9.


Classical eyelid conditioning has been used to great advantage in demonstrating that the cerebellum helps to improve movements through experience, and in identifying the underlying mechanisms. Results from recent studies support the hypotheses that learning occurs in both the cerebellar nucleus and cortex, and that these sites make different contributions. Specifically, results indicate that the cerebellar cortex is responsible for temporally specific learning. A combination of experimental and computational studies has been important for arriving at these conclusions, which seem to be applicable to the broad range of movements to which the cerebellum contributes.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Cerebellum / physiology*
  • Conditioning, Eyelid / physiology*