Multigenic control of Listeria monocytogenes susceptibility in mice

Nat Genet. 2001 Mar;27(3):259-60. doi: 10.1038/85812.


We have used a novel quantitative trait locus model to study the genetics of survival of F2 progeny of susceptible BALB/cByJ and resistant C57BL/6ByJ mice that have been infected with Listeria monocytogenes. This allowed us to map modifiers of L. monocytogenes susceptibility to chromosomes 5 and 13.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Chromosome Mapping
  • Crosses, Genetic
  • Female
  • Listeriosis / genetics*
  • Listeriosis / immunology*
  • Listeriosis / pathology
  • Male
  • Mice
  • Mice, Inbred BALB C
  • Mice, Inbred C57BL
  • Quantitative Trait, Heritable