Mechanisms for ATP-dependent chromatin remodelling

Curr Opin Genet Dev. 2001 Apr;11(2):148-54. doi: 10.1016/s0959-437x(00)00172-6.

Abstract

During the past year, major advances have been made towards understanding the function of ATP-dependent chromatin-remodelling activities both in vitro and in vivo. These suggest that ATP-dependent chromatin-remodelling activities are capable of both altering the structure of individual nucleosomes and acting in concert with other forms of chromatin-modifying enzymes, to regulate the formation and decondensation of chromatin fibres.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Adenosine Triphosphate / metabolism*
  • Animals
  • Chromatin / metabolism*
  • Chromatin / ultrastructure*
  • DNA Helicases / chemistry
  • DNA Helicases / metabolism*
  • Gene Expression Regulation
  • Nucleosomes / metabolism
  • Nucleosomes / ultrastructure

Substances

  • Chromatin
  • Nucleosomes
  • Adenosine Triphosphate
  • DNA Helicases