Primary extracranial meningioma of the mandible: A report of 2 cases and a review of the literature

Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2001 Mar;91(3):338-41. doi: 10.1067/moe.2001.112947.


Three cases of primary extracranial meningioma arising in the jaws have been reported in the English-language literature. The purpose of this report is to document 2 additional cases that arose in the mandible. Both cases occurred in women and appeared as radiolucent lesions. Microscopic examination revealed an unencapsulated tumor composed of uniform spindle-shaped cells arranged in whorls and interconnecting fascicles. Occasional nuclear pseudoinclusions and psammoma bodies were identified. The tumor cells demonstrated immunohistochemical reactivity for epithelial membrane antigen and vimentin. Both cases were treated by surgical excision. Based on previously published examples in the jaws, these neoplasms do not appear to be aggressive.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Aged
  • Female
  • Humans
  • Immunoenzyme Techniques
  • Mandibular Neoplasms / pathology*
  • Mandibular Neoplasms / surgery
  • Meningioma / pathology*
  • Meningioma / surgery