Neural basis of deciding, choosing and acting

Nat Rev Neurosci. 2001 Jan;2(1):33-42. doi: 10.1038/35049054.


The ability and opportunity to make decisions and carry out effective actions in pursuit of goals is central to intelligent life. Recent research has provided significant new insights into how the brain arrives at decisions, makes choices, and produces and evaluates the consequences of actions. In fact, by monitoring or manipulating specific neurons, certain choices can now be predicted or manipulated.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Brain / physiology*
  • Choice Behavior / physiology*
  • Cognition / physiology
  • Decision Making / physiology*
  • Humans
  • Neurons / physiology*
  • Thinking / physiology*