Corneal sensation after correction of myopia by photorefractive keratectomy and laser in situ keratomileusis

J Cataract Refract Surg. 2001 Mar;27(3):370-3. doi: 10.1016/s0886-3350(00)00756-2.


Purpose: To compare the effects of photorefractive keratectomy (PRK) and laser in situ keratomileusis (LASIK) on corneal sensation.

Setting: Ohshima Hospital of Ophthalmology, Fukuoka, Japan.

Methods: Corneal sensation was measured with a Cochet-Bonnet esthesiometer in 35 patients before and 3 days, 1 week, and 1 and 3 months after correction of myopia by PRK (22 patients) or LASIK (13 patients).

Results: After PRK, corneal sensitivity was decreased slightly at 3 days, began to recover at 1 week, and returned to preoperative values at 3 months; none of the changes was statistically significant (P >.05). After LASIK, corneal sensation was significantly decreased at 3 days, 1 week, and 1 month; it recovered slightly at 3 months, although it remained significantly less than preoperatively.

Conclusions: Laser in situ keratomileusis was associated with a negative effect on corneal sensation, which was markedly greater than the effect with PRK and was evident for at least 3 months after surgery.

Publication types

  • Comparative Study

MeSH terms

  • Adolescent
  • Adult
  • Corneal Diseases / diagnosis
  • Corneal Diseases / etiology*
  • Corneal Diseases / physiopathology
  • Diagnostic Techniques, Ophthalmological
  • Female
  • Humans
  • Keratomileusis, Laser In Situ / adverse effects*
  • Lasers, Excimer
  • Male
  • Middle Aged
  • Myopia / surgery*
  • Photorefractive Keratectomy / adverse effects*
  • Sensation Disorders / diagnosis
  • Sensation Disorders / etiology*
  • Sensation Disorders / physiopathology
  • Time Factors