Reduced central serotonergic activity in mania: implications for the relationship between depression and mania

Br J Psychiatry. 1975 Mar:126:241-8. doi: 10.1192/bjp.126.3.241.
No abstract available

MeSH terms

  • Bipolar Disorder / cerebrospinal fluid
  • Bipolar Disorder / drug therapy
  • Bipolar Disorder / metabolism*
  • Brain / metabolism*
  • Depression / cerebrospinal fluid
  • Depression / drug therapy
  • Disease Models, Animal
  • Humans
  • Hydroxyindoleacetic Acid / cerebrospinal fluid
  • Hypnotics and Sedatives / therapeutic use
  • Imipramine / pharmacology
  • Imipramine / therapeutic use
  • Lithium / therapeutic use
  • Methysergide / therapeutic use
  • Monoamine Oxidase Inhibitors / therapeutic use
  • Phenylalanine / analogs & derivatives
  • Phenylalanine / therapeutic use
  • Probenecid
  • Serotonin / metabolism*
  • Tryptophan / cerebrospinal fluid
  • Tryptophan / therapeutic use

Substances

  • Hypnotics and Sedatives
  • Monoamine Oxidase Inhibitors
  • Serotonin
  • Phenylalanine
  • Hydroxyindoleacetic Acid
  • Tryptophan
  • Lithium
  • Imipramine
  • Probenecid
  • Methysergide