Skin occlusion and irritant and allergic contact dermatitis: an overview

H Zhai; H I Maibach

doi:10.1034/j.1600-0536.2001.044004201.x

Skin occlusion and irritant and allergic contact dermatitis: an overview

Contact Dermatitis. 2001 Apr;44(4):201-6. doi: 10.1034/j.1600-0536.2001.044004201.x.

Authors

H Zhai¹, H I Maibach

Affiliation

¹ Department of Dermatology, University of California, School of Medicine, Box 0989, Surge 110, San Francisco, CA 94143-0989, USA.

PMID: 11260234
DOI: 10.1034/j.1600-0536.2001.044004201.x

Abstract

Occlusion, widely used to enhance percutaneous absorption of drugs, also increases penetration of other chemicals and antigens, and hence may exacerbate irritant and allergic contact dermatitis. This overview summarizes the adverse effects of occlusion.

Publication types

Review

MeSH terms

Animals
Dermatitis, Allergic Contact / etiology
Dermatitis, Allergic Contact / physiopathology*
Humans
Irritants / adverse effects*
Occlusive Dressings / adverse effects*
Skin / pathology
Skin / physiopathology*
Water Loss, Insensible / drug effects

Substances

Irritants