Effect of inositol on bulimia nervosa and binge eating

Int J Eat Disord. 2001 Apr;29(3):345-8. doi: 10.1002/eat.1028.


Objectives: This study aimed to determine whether inositol has therapeutic value in patients with bulimia nervosa and binge eating.

Method: A double-blind crossover trial using 18 g inositol versus placebo was performed in 12 patients for 6 weeks in each arm.

Results: Inositol was significantly better than placebo on the Global Clinical Impression, the Visual Analogue Scale, and the Eating Disorders Inventory.

Discussion: Inositol is as therapeutic in patients with bulimia nervosa and binge eating as it is in patients with depression and panic and obsessive-compulsive disorders. This increases its parallelism with serotonin selective reuptake inhibitors.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Bulimia / drug therapy*
  • Cross-Over Studies
  • Double-Blind Method
  • Female
  • Follow-Up Studies
  • Humans
  • Inositol / administration & dosage
  • Inositol / therapeutic use*
  • Male
  • Treatment Outcome


  • Inositol