Laboratory methods in ophthalmic genetics: obtaining DNA from patients

Ophthalmic Genet. 2001 Mar;22(1):49-60. doi: 10.1076/opge.


DNA samples are the fundamental research substrate in genetics. Although methodology and cost-effectiveness in molecular biology have improved dramatically, collecting biological samples and extracting DNA continue to be expensive and time-consuming steps of genetic research. This article reviews the issues surrounding the choice of biological samples for methods of DNA extraction as well as the storage and transport of biological and DNA samples for genetic studies.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • DNA / isolation & purification*
  • Eye Diseases / genetics*
  • Eye Diseases / pathology
  • Informed Consent
  • Molecular Biology / economics
  • Molecular Biology / methods*
  • Ophthalmology / economics
  • Ophthalmology / methods*
  • Specimen Handling


  • DNA