Where Notch and Wnt signaling meet. The presenilin hub
- PMID: 11266476
- PMCID: PMC2195779
- DOI: 10.1083/jcb.152.4.f17
Where Notch and Wnt signaling meet. The presenilin hub
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Presenilin 1 negatively regulates beta-catenin/T cell factor/lymphoid enhancer factor-1 signaling independently of beta-amyloid precursor protein and notch processing.J Cell Biol. 2001 Feb 19;152(4):785-94. doi: 10.1083/jcb.152.4.785. J Cell Biol. 2001. PMID: 11266469 Free PMC article.
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References
-
- Annaert W., De Strooper B. Presenilinsmolecular switches between proteolysis and signal transduction. Trends Neurosci. 1999;22:439–443. - PubMed
-
- Axelrod J.D., Matsuno K., Artavanis-Tsakonas S., Perrimon N. Interaction between Wingless and Notch signaling pathways mediated by dishevelled. Science. 1996;271:1826–1832. - PubMed
-
- Brown M.S., Ye J., Rawson R.B., Goldstein J.L. Regulated intramembrane proteolysisa control mechanism conserved from bacteria to humans. Cell. 2000;100:391–398. - PubMed
-
- Kang D.E., Soriano S., Frosch M.P., Collins T., Naruse S., Sisodia S.S., Leibowitz G., Levine F., Koo E.H. Presenilin 1 facilitates the constitutive turnover of beta-catenindifferential activity of Alzheimer's disease-linked PS1 mutants in the beta-catenin-signaling pathway. J. Neurosci. 1999;19:4229–4237. - PMC - PubMed
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