Inositol phosphates: Does IP(4) run a protection racket?

Curr Biol. 2001 Mar 6;11(5):R172-4. doi: 10.1016/s0960-9822(01)00086-0.

Abstract

The phosphorylation of IP(3) by IP(3) 3-kinase leads to a number of physiological events, most of which are poorly understood. Recent findings about a hitherto unsuspected action of the IP(3) 3-kinase product, IP(4), suggest that the evolution of IP(3) 3-kinase may have even more far-reaching consequences than we thought.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Calcium / metabolism
  • Inositol 1,4,5-Trisphosphate / metabolism*
  • Inositol Phosphates / metabolism*
  • Phosphotransferases (Alcohol Group Acceptor) / metabolism*
  • Receptors, Cytoplasmic and Nuclear / metabolism

Substances

  • Inositol Phosphates
  • Receptors, Cytoplasmic and Nuclear
  • inositol-1,3,4,5-tetrakisphosphate receptor
  • inositol-1,3,4,5-tetrakisphosphate
  • Inositol 1,4,5-Trisphosphate
  • Phosphotransferases (Alcohol Group Acceptor)
  • Inositol 1,4,5-trisphosphate 3-kinase
  • Calcium