Maternal transmission of nicotine dependence: psychiatric, neurocognitive and prenatal factors

Am J Addict. Winter 2001;10(1):16-29. doi: 10.1080/105504901750160420.


This paper reviews the literature on maternal influences on smoking behaviors of offspring from the perspective of neuropsychiatric deficits that may be transmitted from mother to child. In particular, we review what is known regarding associations between: (1) in-utero exposure to smoking, (2) adolescent neurocognitive functioning and psychiatric comorbidity, and (3) the patterns of smoking and progression of nicotine dependence. Furthering our knowledge of these differences in susceptibility to nicotine dependence among youth will provide additional avenues for prevention and intervention efforts targeted toward those at high risk for dependence.

Publication types

  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Adolescent
  • Adolescent Behavior*
  • Adult
  • Child
  • Cognition Disorders / etiology*
  • Comorbidity
  • Female
  • Humans
  • Personality Disorders
  • Pregnancy
  • Prenatal Exposure Delayed Effects*
  • Risk Factors
  • Smoking / adverse effects*
  • Tobacco Use Disorder / genetics*
  • Tobacco Use Disorder / physiopathology