[Morphofunctional changes in the olfactory bulb after odor stimuli deprivation (II). Histochemical study]

Acta Otorrinolaringol Esp. 2000 Nov-Dec;51(8):665-75.
[Article in Spanish]


By histochemical and immunohistochemical methods we study the effects that has the odorous stimuli privation in the first day after the birth on the activity of the olfactory bulb of the gerbil (Meriones Unguiculatus). This sensory deprivation of stimuli causes drastic reductions in given activities (Tyrosine Hydroxylase) no altering other (DOPA-Decarboxylase). This indicates that the functional ripeness of given enzymatic systems specify of an integrity of their sensorial afferences, while it is not necessary for the normal activity of other enzymes even within the same cell.

MeSH terms

  • Animals
  • Biomarkers
  • Calbindins
  • Female
  • Gerbillinae
  • Immunohistochemistry
  • Male
  • NADP
  • Nerve Tissue Proteins / analysis
  • Neurons / metabolism*
  • Neurotransmitter Agents / metabolism*
  • Odorants*
  • Olfactory Bulb / cytology
  • Olfactory Bulb / metabolism*
  • Olfactory Bulb / pathology*
  • S100 Calcium Binding Protein G / analysis
  • Sensory Deprivation / physiology*
  • Smell / physiology
  • Tyrosine 3-Monooxygenase / analysis


  • Biomarkers
  • Calbindins
  • Nerve Tissue Proteins
  • Neurotransmitter Agents
  • S100 Calcium Binding Protein G
  • NADP
  • Tyrosine 3-Monooxygenase