Cavernous sinus thrombophlebitis in children

Pediatr Neurol. 2001 Feb;24(2):123-7. doi: 10.1016/s0887-8994(00)00255-1.


Eight Thai patients less than 15 years of age who were diagnosed with cavernous sinus thrombophlebitis at Ramathibodi Hospital, Bangkok, Thailand over the past 30 years were reviewed retrospectively. The predisposing infections and causative microorganisms were similar to previous reports in children and adults. Despite severe neurologic dysfunction during admission, including blindness, there was neither death nor severe permanent deficit found in the majority of the patients. Only one patient experienced mild hemiparesis caused by cerebral infarction, which was secondary to this condition. Early recognition of this condition, the appropriate selection of empirical antibiotic therapy, and the awareness of associated complication were the key factors leading to excellent outcome.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Anti-Bacterial Agents*
  • Brain / blood supply
  • Brain / diagnostic imaging
  • Brain / pathology*
  • Carotid Arteries / diagnostic imaging*
  • Cavernous Sinus Thrombosis* / drug therapy
  • Cavernous Sinus Thrombosis* / microbiology
  • Cavernous Sinus Thrombosis* / pathology
  • Cerebral Angiography
  • Child
  • Child, Preschool
  • Diagnosis, Differential
  • Drug Therapy, Combination / therapeutic use*
  • Female
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Retrospective Studies
  • Treatment Outcome


  • Anti-Bacterial Agents