doi: 10.1038/86042.
Morphological correlates of functionally defined synaptic vesicle populations
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- PMID: 11276229
- DOI: 10.1038/86042
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Morphological correlates of functionally defined synaptic vesicle populations
Nat Neurosci.
2001 Apr.
Abstract
By combining photoconversion of FM1-43-stained vesicles and electron microscopy of hippocampal synapses, we find evidence that the population of morphologically docked synaptic vesicles corresponds to the release-ready neurotransmitter quanta. Furthermore, those synaptic vesicles that are participating in cycles of exo- and endocytosis tend to be closer to the active zone than vesicles that are being held in reserve.
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