Seeking a vaccine against Coccidioides immitis and serologic studies: expectations and realities

Fungal Genet Biol. 2001 Feb;32(1):1-9. doi: 10.1006/fgbi.2000.1243.


The studies reported in this review indicate that, whereas the expectations from the molecular approach help to excite and enlighten us, the realities suggest that even some less modern approaches may provide the necessary practical solutions to problems of serology and vaccination against coccidioidomycosis. Concurrent conduct of the two approaches should maximize the chances for success.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Coccidioides / immunology
  • Coccidioides / isolation & purification
  • Coccidioides / pathogenicity
  • Coccidioidomycosis / blood
  • Coccidioidomycosis / immunology
  • Coccidioidomycosis / prevention & control*
  • Complement Fixation Tests
  • Fungal Vaccines* / administration & dosage
  • Humans
  • Immunity, Active
  • Precipitin Tests
  • Vaccination


  • Fungal Vaccines