New eudesmane sesquiterpenes from the root of Lindera strychnifolia

I Kouno; A Hirai; A Fukushige; Z H Jiang; T Tanaka

doi:10.1021/np000154s

New eudesmane sesquiterpenes from the root of Lindera strychnifolia

J Nat Prod. 2001 Mar;64(3):286-8. doi: 10.1021/np000154s.

Authors

I Kouno¹, A Hirai, A Fukushige, Z H Jiang, T Tanaka

Affiliation

¹ Faculty of Pharmaceutical Sciences, Nagasaki University, Bunkyo-machi 1-14, Nagasaki 852-8521, Japan. ikouno@net.nagasaki-u.ac.jp

PMID: 11277740
DOI: 10.1021/np000154s

Abstract

Strychnistenolide (1) and its acetate 2 were isolated from the root of Lindera strychnifolia, along with a novel rearranged type of secoeudesmane, strychnilactone (3). Their structures were elucidated by extensive analysis of their NMR spectra, including 2D NMR techniques, together with an X-ray analysis for 3. Strychnistenolide exists as a single stereoisomer in CHCl(3), but in pyridine is epimerized.

MeSH terms

China
Drugs, Chinese Herbal / chemistry*
Lauraceae / chemistry*
Naphthalenes / chemistry
Plant Extracts / chemistry
Plant Roots / chemistry
Plants, Medicinal / chemistry
Sesquiterpenes / chemistry
Sesquiterpenes / isolation & purification*
Sesquiterpenes, Eudesmane*

Substances

Drugs, Chinese Herbal
Naphthalenes
Plant Extracts
Sesquiterpenes
Sesquiterpenes, Eudesmane
strychnilactone
strychnistenolide
eudesmane