Gender reassignment and assisted reproduction: present and future reproductive options for transsexual people

Hum Reprod. 2001 Apr;16(4):612-4. doi: 10.1093/humrep/16.4.612.


Transsexual people who want transition to their desired gender have to undergo hormonal and surgical treatments, which lead to irreversible loss of their reproductive potential. This paper argues that transsexual people should be offered the same options as any person that risks losing their germ cells because of treatment for a malignant disease. Indeed, transsexual women (male-to-female transsexual patients) may be given the option to store spermatozoa before they start hormonal therapy, so that their gametes may be used in future relationships. This may be especially important for the many transsexual women who identify as lesbians after their transition. Conversely, transsexual men (female-to-male transsexual patients) may be offered storage of oocytes or ovarian tissue, possibly obtained at the time of their oophorectomy. Current technology offers transsexual people the possibility to obtain children who are genetically their own in their future relationships and the option of gamete banking should therefore be discussed before starting hormonal and surgical reassignment treatment. This is particularly important for transsexual people who are diagnosed and treated at a young age.

Publication types

  • Review

MeSH terms

  • Animals
  • Embryo, Mammalian
  • Female
  • Forecasting
  • Humans
  • Oocytes
  • Ovary
  • Reproductive Techniques / legislation & jurisprudence*
  • Reproductive Techniques / trends
  • Semen Preservation
  • Tissue Preservation*
  • Transsexualism*