Genetic linkage of childhood atopic dermatitis to psoriasis susceptibility loci

Nat Genet. 2001 Apr;27(4):372-3. doi: 10.1038/86867.


We have carried out a genome screen for atopic dermatitis (AD) and have identified linkage to AD on chromosomes 1q21, 17q25 and 20p. These regions correspond closely with known psoriasis loci, as does a previously identified AD locus on chromosome 3q21. The results indicate that AD is influenced by genes with general effects on dermal inflammation and immunity.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Child
  • Dermatitis, Atopic / genetics*
  • Genetic Linkage*
  • Genetic Predisposition to Disease*
  • Humans
  • Psoriasis / genetics*