Plant sterols and their derivatives: the current spread of results

Nutr Rev. 2001 Jan;59(1 Pt 1):21-4. doi: 10.1111/j.1753-4887.2001.tb01901.x.


Whereas the cholesterol-lowering action of plant sterols and their derivatives has been well established, more recent results have produced new information concerning the similar effects of various mixtures and dose-response relationships. Moreover, although these materials have generally been viewed as safe for long-term use in almost all sectors of the population, some concerns remain regarding the impact of phytosterol consumption on other lipid-soluble nutrients, which need to be further addressed. Further work is also required to define the relationship between plant sterol consumption, circulating sterol levels, and risk of certain cancers.

Publication types

  • Review

MeSH terms

  • Dose-Response Relationship, Drug
  • Humans
  • Neoplasms / etiology
  • Phytosterols / administration & dosage*
  • Phytosterols / adverse effects
  • Safety
  • Sterols / blood*
  • Treatment Outcome


  • Phytosterols
  • Sterols