Second-order selection in bacterial evolution: selection acting on mutation and recombination rates in the course of adaptation

Res Microbiol. Jan-Feb 2001;152(1):11-6. doi: 10.1016/s0923-2508(00)01163-3.

Abstract

The increase in genetic variability of a population can be selected during adaptation, as demonstrated by the selection of mutator alleles. The dynamics of this phenomenon, named second-order selection, can result in an improved adaptability of bacteria through regulation of all facets of mutation and recombination processes.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Adaptation, Physiological / genetics*
  • Bacteria / genetics*
  • Bacteria / growth & development
  • Biological Evolution*
  • Mutation / genetics*
  • Recombination, Genetic / genetics
  • Selection, Genetic*