Inflammatory pseudotumor of the trachea

J Pediatr Surg. 2001 Apr;36(4):631-4. doi: 10.1053/jpsu.2001.22306.


Primary tracheal tumors are extremely rare, and the majority of them are malignant. Inflammatory pseudotumor is a benign, tumorlike lesion, most likely of a reactive nature. Its basic morphologic characteristic is spindle cell (myoblasts and fibroblasts) proliferation with a variable number and type of inflammatory cells. A case of intratracheal inflammatory pseudotumor in a 14-year-old boy is presented together with a review of all similar lesions in the available literature. The discussion includes the presentation of tracheal tumors, their basic morphologic and immunohistochemical characteristics, and treatment modalities that are available. The surgeon must exercise caution not to perform radical surgery based on the initial pathologic diagnosis from the intraoperative frozen section, because the prognosis of these benign lesions generally is excellent. This is the second reported case of intratracheal inflammatory pseudotumor successfully endoscopically vaporized using a CO(2) laser, which is an excellent alternative in cases in which surgical treatment is feasible. J Pediatr Surg 36:631-634.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adolescent
  • Biopsy, Needle
  • Follow-Up Studies
  • Granuloma, Plasma Cell / diagnostic imaging
  • Granuloma, Plasma Cell / pathology*
  • Granuloma, Plasma Cell / surgery*
  • Humans
  • Laser Therapy / methods*
  • Male
  • Radiography
  • Tracheal Diseases / diagnostic imaging
  • Tracheal Diseases / pathology*
  • Tracheal Diseases / surgery*
  • Treatment Outcome