Computational methods for gene annotation: the Arabidopsis genome

Curr Opin Biotechnol. 2001 Apr;12(2):126-30. doi: 10.1016/s0958-1669(00)00185-3.


Since the structure of the DNA molecule was identified half a century ago, the complete genome sequence has been determined for 37 prokaryotes and several eukaryotes. With the exponential growth of genetic information, bioinformatics has attempted to predict gene locations and functions in cyberspace prior to experimental confirmation at the bench.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Arabidopsis / genetics*
  • Base Sequence
  • Computational Biology / methods*
  • Genes, Plant
  • Genome, Plant*
  • Molecular Sequence Data
  • Quality Control
  • Sequence Homology, Nucleic Acid
  • Software