An anti-inflammatory principle from cactus

Fitoterapia. 2001 Mar;72(3):288-90. doi: 10.1016/s0367-326x(00)00287-2.


In previous studies, the ethanol extract of cactus (Opuntia ficus-indica) showed potent anti-inflammatory action. In the present study, following fractionation of the methanol extract of cactus stems guided by adjuvant-induced chronic inflammation model in mice, an active anti-inflammatory principle has been isolated and identified as beta-sitosterol.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Anti-Inflammatory Agents, Non-Steroidal / pharmacology*
  • Drugs, Chinese Herbal / pharmacology*
  • Granuloma / prevention & control*
  • Male
  • Mice
  • Mice, Inbred ICR
  • Plants, Medicinal*
  • Sitosterols / pharmacology*


  • Anti-Inflammatory Agents, Non-Steroidal
  • Drugs, Chinese Herbal
  • Sitosterols
  • gamma-sitosterol