Atomic structures at last: the ribosome in 2000

Curr Opin Struct Biol. 2001 Apr;11(2):144-54. doi: 10.1016/s0959-440x(00)00184-6.


Last year, atomic structures of the 50S ribosomal subunit from Haloarcula marismortui and of the 30S ribosomal subunit from Thermus thermophilus were published. A year before that, a 7.8 A resolution electron density map of the 70S ribosome from T. thermophilus appeared. This information is revolutionizing our understanding of protein synthesis.

Publication types

  • Review

MeSH terms

  • Binding Sites
  • Crystallography / methods*
  • Microscopy, Atomic Force
  • Microscopy, Electron / methods*
  • Peptide Elongation Factor G / chemistry
  • Peptide Elongation Factor G / metabolism
  • RNA, Transfer / metabolism
  • Ribosomes / chemistry*
  • Ribosomes / metabolism*


  • Peptide Elongation Factor G
  • RNA, Transfer